Novel α-arylnitriles synthesis via Ni-catalyzed cross-coupling of α-bromonitriles with arylboronic acids under mild conditions.

نویسندگان

  • Yingying Yang
  • Shan Tang
  • Chao Liu
  • Huimin Zhang
  • Zhexun Sun
  • Aiwen Lei
چکیده

An applicable and easy-handling Ni-catalyst can be used to promote direct arylation of α-bromonitriles with various arylboronic acids to construct α-arylnitriles under mild conditions. The methodology tolerates β-hydrogens and functional groups in the substrates.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 9 15  شماره 

صفحات  -

تاریخ انتشار 2011